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Belli M, Barone L, Bellia A, et al
With significant or rapid weight loss, particularly when driven by GLP-1 drugs, several mechanisms converge: Loss of underlying fat volume removes structural support Collagen and elastin fibres become stretched and fragmented Speed of weight loss outpaces skin contraction While some rebound occurs naturally, significant laxity can be permanent, especially after large weight reductions
In another phase II trial with 52 people with clinical evidence of NASH, liraglutide 1.8 mg treatment led to histological improvement of NASH [79]
CD4 is thought to have arisen relatively recently in teleost fish following duplication of a two Ig domain-containing ancestral gene, CD4REC (Laing et al., 2B) (Laing et al., 2A shows only mammals
Clear to pale yellow is the expected range